Despite the global impact of the coronavirus disease 2019 pandemic, the question of whether mandated interventions have similar economic and public health effects as spontaneous behavioural change remains unresolved. Addressing this question, and understanding differential effects across socioeconomic groups, requires building quantitative and fine-grained mechanistic models.

Here we introduce a data-driven, granular, agent-based model that simulates epidemic and economic outcomes across industries, occupations and income levels.

We validate the model by reproducing key outcomes of the first wave of coronavirus disease 2019 in the New York metropolitan area. The key mechanism coupling the epidemic and economic modules is the reduction in consumption due to fear of infection.

In counterfactual experiments, we show that a similar trade-off between epidemic and economic outcomes exists both when individuals change their behaviour due to fear of infection and when non-pharmaceutical interventions are imposed.

Low-income workers, who perform in-person occupations in customer-facing industries, face the strongest trade-off.

M. Pangallo, A. Aleta, R. M. Del Rio Chanona, A. Pichler, D. Martín-Corral, M. Chinazzi, F. Lafond, M. Ajelli, E. Moro, Y. Moreno, A. Vespignani, J. D. Farmer, The unequal effects of the health-economy tradeoff during the COVID-19 pandemic, Nature Human Behaviour (2023).